Accession 222
Title Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo
Summary A protein array-based analysis of the mitogen-activated protein kinase pathway revealed that melanoma cells overexpressing PDGF-Ralpha show a strong reduction of c-Jun phosphorylated in serine 63 and of protein phosphatase 2A/Balpha and a marked increase of p38gamma, mitogen-activated protein kinase kinase 3, and signal regulatory protein alpha1 protein expression.
Journal Neoplasia
Publish date August, 2009
Corresponding Author Antonio Facchiano
E-mail antoniofacchiano@yahoo.it
Array Type Antibody array
Species Homo sapiens
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:19649203