Accession 222
Title Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo
Summary A protein array-based analysis of the mitogen-activated protein kinase pathway revealed that melanoma cells overexpressing PDGF-Ralpha show a strong reduction of c-Jun phosphorylated in serine 63 and of protein phosphatase 2A/Balpha and a marked increase of p38gamma, mitogen-activated protein kinase kinase 3, and signal regulatory protein alpha1 protein expression.
Journal Neoplasia
Publish date August, 2009
Corresponding Author Antonio Facchiano
Array Type Antibody array
Species Homo sapiens
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:19649203