Accession 249
Title Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells
Summary Microarray analyses implicated NICD-induced p63 down-regulation in loss of matrix adhesion. In addition, a reverse-phase protein array-based analysis and subsequent loss-of-function studies identified STAT3 as a dominant downstream mediator of the NICD-induced outgrowth.
Journal Proc Natl Acad Sci U S A.
Publish date March, 2010
Corresponding Author Joan S. Brugge
E-mail joan_brugge@hms.harvard.edu
Array Type Reverse phase protein array
Species Homo sapiens
Raw data link

Gene Expression Omnibus (www.ncbi.nlm.nih.gov/geo, GSE20285 and GSE20286).

Link to PubMed

PubMed ID:20194747