| Accession |
260 |
| Title |
Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium |
| Summary |
We now hypothesize that activation of NOD2 in the newborn intestine inhibits TLR4, and that failure of NOD2 signaling leads to NEC through increased TLR4-mediated enterocyte apoptosis. A protein array was performed on NOD2-activated enterocytes to identify novel effector molecules involved. |
| Journal |
Gastroenterology |
| Publish date |
May, 2010 |
| Corresponding Author |
David J. Hackam |
| E-mail |
david.hackam@chp.edu |
| Array Type |
Antibody array |
| Species |
Homo sapiens; Mus musculus |
| Raw data link |
No relevant experiment link!
|
| Link to PubMed |
PubMed ID:20580721
|
