| Accession |
273 |
| Title |
NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols |
| Summary |
We retrospectively investigated the relevance of NOTCH1/FBXW7 mutations for pediatric T-ALL patients enrolled on Dutch Childhood Oncology Group (DCOG) ALL7/8 or ALL9 or the German Co-Operative Study Group for Childhood Acute Lymphoblastic Leukemia study (COALL-97) protocols. Reverse-phase protein microarray data confirmed that NOTCH1 and FBXW7 mutations resulted in increased intracellular NOTCH1 levels in primary T-ALL biopsies. |
| Journal |
Leukemia |
| Publish date |
September, 2010 |
| Corresponding Author |
JPP Meijerink |
| E-mail |
j.meijerink@erasmusmc.nl |
| Array Type |
Reverse phase protein array |
| Species |
Homo sapiens |
| Raw data link |
No relevant experiment link!
|
| Link to PubMed |
PubMed ID:20861909
|
