| Accession | 345 |
| Title | Monoclonal antibody-induced ErbB3 receptor internalization and degradation inhibits growth and migration of human melanoma cells |
| Summary | In this study, we have evaluated the potential therapeutic efficacy of a set of three recently generated anti-human ErbB3 monoclonals, A2, A3 and A4, in human primary melanoma cells. Then, fine epitope mapping studies through a peptide array show that inhibiting vs. non-inhibiting antibodies have a dramatically different mode of binding to the to the receptor extracellular domain. |
| Journal | Cell Cycle |
| Publish date | April, 2012 |
| Corresponding Author | Gennaro Ciliberto |
| gennaro54.ciliberto@gmail.com | |
| Array Type | Peptide array |
| Species | Homo sapiens |
| Raw data link | No relevant experiment link! |
| Link to PubMed |