Accession 382
Title Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke
Summary This study examines the EMT process in human bronchial epithelial cells (HBECs) from non-smokers, smokers and patients with COPD as well as the in vitro effect of cigarette smoke extract (CSE) on EMT. HBECs from non-smokers (n=5), smokers (n=12) and patients with COPD (n=15) were collected to measure the mesenchymal markers α-smooth muscle actin, vimentin and collagen type I and the epithelial markers E-cadherin, ZO-1 and cytokeratin 5 and 18 by real time-PCR and protein array
Journal Thorax.
Publish date January, 2013
Corresponding Author Milara J
Array Type Antibody array
Species Homo sapiens
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:23299965