| Accession | 386 |
| Title | Profiling pathway-specific novel therapeutics in preclinical assessment for central nervous system atypical teratoid rhabdoid tumors (CNS ATRT): favorable activity of targeting EGFR- ErbB2 signaling with lapatinib |
| Summary | Target modulation, antibody array analysis, drug combination and in vivo xenograft studies were performed on one of the pathway inhibitors found in this screening. Approximately 20% of agents in the library showed activity with IC(50) values of 1 μM or less and many showed IC(50) values less than 0.05 μM. |
| Journal | Mol Oncol. |
| Publish date | January, 2013 |
| Corresponding Author | Aru Narendran |
| a.narendran@ucalgary.ca | |
| Array Type | Antibody array |
| Species | Homo sapiens |
| Raw data link | No relevant experiment link! |
| Link to PubMed |