Accession 508
Title IgM Abs to Apoptosis-associated Determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells
Summary Herein, we show that the immune response to neoantigenic determinants on apoptotic thymocytes is dominated by Abs to oxidation-associated Ags, phosphorylcholine (PC), a head group that becomes exposed during programmed cell death, and malondialdehyde (MDA), a reactive aldehyde degradation product of polyunsaturated lipids produced following exposure to reactive oxidation species.
Journal J Immunol
Publish date May, 2009
Corresponding Author Gregg J. Silverman
E-mail gsilverman@ucsd.edu
Array Type Proteome array
Species Mus musculus
Raw data link

PMDE63

Link to PubMed

PubMed ID:19414754