Accession 72
Title Tudor, MBT and chromo domains gauge the degree of lysine methylation
Summary Here, we describe a protein-array approach for identifying methyl-specific interacting proteins. We found that not only chromo domains but also tudor and MBT domains bind to methylated peptides from the amino-terminal tails of histones H3 and H4. Binding specificity observed on the protein-domain microarray was corroborated using peptide pull-downs, surface plasma resonance and far western blotting.
Journal EMBO Rep.
Publish date April, 2006
Corresponding Author Mark T Bedford
E-mail mtbedford@mdanderson.org
Array Type Proteome array
Species Muti-species
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:16415788